{"id":6184,"date":"2021-10-11T13:56:19","date_gmt":"2021-10-11T11:56:19","guid":{"rendered":"https:\/\/www.bartmaes.eu\/?p=6184"},"modified":"2021-11-17T13:32:19","modified_gmt":"2021-11-17T12:32:19","slug":"sources-and-references-about-polyphenols","status":"publish","type":"post","link":"https:\/\/www.bartmaes.eu\/en\/polyphenols\/sources-and-references-about-polyphenols\/","title":{"rendered":"Resources and references on polyphenols."},"content":{"rendered":"\n<p><strong><br\/>Several articles on polyphenols and olive leaf extract. Written by Bart Maes. The organic veggie man. His articles always have a strong scientific background. No nonsense and no chicken talk.<\/strong><\/p>\n\n<p>Special thanks to: Professor Benlemlih M, Dr. Ghanam J and Professor H. Joyeux. In their work Polyphenols in olive oil, plants and olive leaf extracts, invaluable for health<br\/><br\/>Aletaha D, Neogi T., Silman A., Funovits J., Felson D., Bingham III, CO, <em>et al.<\/em> The 2010 American College of Rheumatology\/European<br\/>League Against Rheumatism Classification Criteria for Rheumatoid Arthritis. <em>Ann. rheumatism. <\/em>2010 ; 69: 1580-1588.<br\/>Beauchamp GK, Russell SJK, Diane M., Jianming L., Jana P., Qiang H., <em>et al.<\/em> Phytochemistry: Ibuprofenlike activity in extravirgin olive oil. <em>Nature<\/em> 2005 ; 437 : 45\u201346.<br\/>Berglin E., Kokkonen H., Einarsdottir E., Agren A., Rantapaa Dahlqvist S., Influence of female hormonal factors, in relation<br\/>to autoantibodies and genetic markers, on the development of rheumatoid arthritis in northern Sweden : a case-control study. <em>scan. J. Rheumatol. <\/em>2010 ; 39 :454-60.<br\/>Boissier MC, Semerano L., Challal S., Saidenberg-Kermanac&#8217;h N., Falgarone G., Rheumatoid arthritis : from autoimmunity to synovitis and joint destruction : a review. <em>J. Autoimmune<\/em> 2012 ; 39 : 222\u20138.<br\/>Camargo A., Rangel-Zuniga O., Haro C., Meza- Miranda E., Pena-Orihuela P., Meneses M., <em>et al.<\/em> Olive oil phenolic compounds decrease the postprandial inflammatory response by reducing postprandial plasma lipopolysaccharide levels. <em>food chem.<\/em> 2014 ; 162 : 161-171.<br\/>Bitler CM, Viale TM, Damaj B., Crea R., Hydrolyzed Olive Vegetation <br\/>Water in Mice Has Anti-Inflammatory Activity. <em>J. Nutr.<\/em> 2005 ; 135: 1475-1479.<br\/>Cernadas L., Rodriguez-Romero B., Carballo-Costa L., Importance of nutritional treatment in the inflammatory process of rheumatoid arthritis patients ; a review. <em>Nutr. landlady <\/em>2014 ; 29 : 237\u201345.<br\/>Covas MI, de la Torre K., Farre-Albaladejo M., Kaikkonen J., Fito M., Lopez-Sabater C., <em>et al.<\/em> Postprandial LDL phenolic content and LDL oxidation are modulated by olive oil phenolic compounds in human. <em>Free Radic. bio. med. <\/em>2006 ; 40 : 608\u201316.<br\/>DeLoach LJ, Higgins MS, Caplan AB, Stiff JL, The visual analog scale in the immediate postoperative period : intra subject variability and correlation with a numeric scale. <em>anesthetic. analog.<\/em> 1998 ; 86 : 102\u2013106.<br\/>Eriksson JK, Neovius M., Ernestam S., Lindblad S., Simard JF, Askling J., 2013. Incidence of rheumatoid arthritis in Sweden : a nationwide population-based assessment of incidence, its determinants, and treatment penetration. <em>Arthritis Care Res.<\/em> 2013 ; 65: 870-878.<br\/>Estruch R. Anti-inflammatory effects of the Mediterranean diet : the experience of the PREDIMED study. <em>proc. Nutr. social. <\/em>2010 ; 69: 333\u201340.<br\/>Estruch, R., Martinez-Gonzalez, MA, Corella, D., Salas-Salvado J, RuizGutierrez V, Covas MI, <em>et al.<\/em> Effects of a Mediterranean-Style Diet on Cardiovascular Risk Factors: A Randomized Trial. <em>Ann. Internal. med. <\/em>2006 ; 145: 1-11.<br\/>Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). <em>JAMA<\/em> 2001 ; 285 : 2486-2497.<br\/>Firestein, G. Evolving concepts of rheumatoid arthritis. Nature 423, 356\u2013361 (2003). <br\/>Fito M, Cladellas M, Torre R, Marti J, Munoz D, Schroder H, <em>et al.,<\/em> Anti-inflammatory effect of virgin olive oil in stable coronary disease patients : a randomized, crossover, controlled trial. <em>EUR. J. Clin. Nutr. <\/em>2007 ; 62 : 570\u2013574.<br\/>Fortes C, Garcia-Vilas J, Quesada A, Medina M. Evaluation of the anti-angiogenic potential of hydroxytyrosol and tyrosol, two bio-active phenolic compounds of extra virgin olive oil, in endothelial cell cultures. <em>food chem. <\/em>2012 ; 134 : 134\u2013140.<br\/>Giner E, Andujar I, Recio M, Rios J, Cerda-Nicolas J, Giner R. Oleuropein ameliorates acute colitis in mice. <em>J. Agric. food<\/em> <em>Chem. <\/em>2011 ; 59: 12882\u201392.<br\/>Glossop JR, Dawes PT, Mattey DL. Association between cigarette smoking and release of tumor necrosis factor alpha and its soluble receptors by peripheral blood mononuclear cells in patients with rheumatoid arthritis. <em>Rheumatology<\/em> (Oxford) 2006 ; 45: 1223-1229.<br\/>Helmick CG, Felson DT, Lawrence RC, Gabriel S, Hirsch R, Kwoh CK, <em>et al.<\/em> Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. <em>Arthritis Rheum.<\/em> 2008 ; 58:15-25.<br\/>Hinson R, Williams J, Shacter E. Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: possible role of cyclooxygenase-2. <em>proc. natl. sci. academy. <\/em>1996 ; 93 : 4885\u20134890.<br\/>Hu T, He XWW, Jiang JGG, Xu XLL. Hydroxytyrosol and its potential therapeutic effects : a review. <em>J. Agric. food chem. <\/em>2014 ; 62: 1449\u201355.<br\/>Inoue H, Takamori M, Shimoyama Y, Ishibashi0 H, Yamamoto S, Koshihara Y. Regulation by PGE2 of the production of interleukin-6, macrophage colony stimulating factor, and vascular endothelial growth factor in human synovial fibroblasts. <em>Bro. J. Clin.<\/em> <em>Pharmacol. <\/em>2002 ; 136: 287-295.<br\/>Smolen JS, and Redlich K. Rheumatoid arthritis. In Rose N &amp; Mackay I (Eds): <em>The Autoimmune Diseases<\/em> (Fifth Edition); 2014. p. 511-523.<br\/>Kamei D, Yamakawa K, Takegoshi Y, Mikami-Nakanishi M, Nakatani Y, Oh-Ishi S, <em>et al.<\/em> Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin E synthase-1. <em>J. Biol. Chem. <\/em>2004 ; 279: 33684-95.<br\/>Killeen M, Linder M, Pontoniere P, Crea R. NF-\u03ba\u03b2 signaling and chronic inflammatory diseases : exploring the potential of natural products to drive new therapeutic opportunities. <em>Drug Discov.<\/em> <em>Today<\/em> 2014 ; 19: 373-378.<br\/>Landre-Beauvais AJ. Doit-on admettre une nouvelle espece de Goutte sous la denomination de Goutte, Asthenique Primitive ? <em>an. VIII<\/em>, Paris, Brisson 1800.<br\/>Lu Y, Wahl LM. Oxidative stress augments the production of matrix metalloproteinase-1, cyclooxygenase-2, and prostaglandin E2 through enhancement of NF-kappa activity in lipopolysaccharide-activated human primary monocytes. <em>J. Immunol. <\/em>2005 ; 175 : 5423\u20139. <br\/>Lu B, Hiraki L, Sparks JA, Malspeis S, Chen CY, Awosogba JA, <em>et<\/em> <em>al<\/em> . Being overweight or obese and risk of developing rheumatoid arthritis among women : a prospective cohort study. <em>Ann.<\/em> <em>rheumatism. this. <\/em>2014 ; 73: 205-459.<br\/>Maiuri M, Stefano D, Meglio P, Irace C, Savarese M, Sacchi R, <em>et<\/em> <em>al.<\/em> Hydroxytyrosol, a phenolic compound from virgin olive oil, prevents macrophage activation. <em>Naunyn Schmiedebergs Arc.h<\/em> <em>Pharmacol.<\/em> 2005 ; 371: 457-465.<br\/>Makarov S. NF-kappa in rheumatoid arthritis : a pivotal regulator of inflammation, hyperplasia, and tissue destruction. <em>Arthritis<\/em> <em>Res.<\/em> 2001 ; 3 : 200\u2013206.<br\/>Mattey DL, Dawes PT, Clarke S, Fisher J, Brownfield A, Thomson W, <em>et al.<\/em> Relationship among the HLADRB1 shared epitope smoking and rheumatoid factor production in rheumatoid arthritis. <em>Arthritis Rheumatism.<\/em> 2002 ; 47: 403-407.<br\/>Packard CJ, Bezlyak V, McLean JS, Batty GD, Ford I, Burns H, <em>et<\/em> <em>al.<\/em> Early life socioeconomic adversity is associated in adult life with chronic inflammation, carotid atherosclerosis, poorer lung function and decreased cognitive performance : a cross-sectional, population-based study. <em>BMC Public Health<\/em> 2011 ;11, 42.<br\/>Page TH, Turner JJ, Brown AC, Timms EM, Inglis JJ, Brennan FM, <em>et al.<\/em> Nonsteroidal antiinflammatory drugs increase TNF production in rheumatoid synovial membrane cultures and whole blood. <em>J. Immunol.<\/em> 2010 ; 185 : 3694\u20133701.<br\/>Park Y, Lee A, Shim SC, Lee J, Choe JY, Ahn H, <em>et al.<\/em> Effect of n-3 polyunsaturated fatty acid supplementation in patients with rheumatoid arthritis : a 16-week randomized, double-blind, placebo-controlled, parallel-design multicenter study in Korea. <em>j.<\/em> <em>Nutr. biochem. <\/em>2013 ; 24 : 1367\u201372.<br\/>Pettit AR, Ji H, von Stechow D, Muller R, Goldring SR, Choi Y, <em>et<\/em> <em>al.<\/em> TRANCE\/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. <em>am. J. Pathol. <\/em>2001 ; 159 : 1689\u20131699.<br\/>Prochazkova M, Zanvit P, Dole\u017eal T, Proke\u0161ova L, Kr\u0161iak M. Increased gene expression and production of spinal cyclooxygenase 1 and 2 during experimental osteoarthritis pain. <em>Physiol. res<\/em>. 2009 ; 58: 419-25.<br\/>Richard N, Arnold S, Hoeller U, Kilpert C, Wertz K, Schwager J. Hydroxytyrosol Is the Major Anti-Inflammatory Compound in Aqueous Olive Extracts and Impairs Cytokine and Chemokine Production in Macrophages. <em>Planta Medica<\/em> 2011 ; 77 : 1890-1897.<br\/>Rosignoli P, Fuccelli R, Fabiani R, Servili M, Morozzi G. Effect of olive oil phenols on the production of inflammatory mediators in freshly isolated human monocytes. <em>J. Nutr. biochem. <\/em>2013 ; 24:1513-1519.<br\/>Salminen E, Heikkila S, Poussa T, Lagstrom H, Saario R, Salminen S, <em>et al.<\/em> Female patients tend to alter their diet following the diagnosis of rheumatoid arthritis and breast cancer. <em>Prev. med.<\/em> 2002 ; 34: 529-35.<br\/>Sanchez-Fidalgo S, Sanchez de Ibarguen L, Cardeno A, Alarcon de la Lastra C. Influence of extra virgin olive oil diet enriched with hydroxytyrosol in a chronic DSS colitis model. <em>EUR. J. Nutr.<\/em> 2011 ; 51 : 497\u2013506.<br\/>Scher J, Pillinger M, Abramson S. Nitric oxide synthases and osteoarthri. <em>curr. Rheumatol. Rep. <\/em>2007 ; 9:9-15.<br\/>Scoditti E, Calabriso N, Massaro M, Pellegrino M, Storelli C, Martines G, <em>et al.<\/em> Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells : a potentially protective mechanism in atherosclerotic vascular disease and cancer. <em>Arch.<\/em> <em>biochem. biophys. <\/em>2012 ; 527 : 81\u201389.<br\/>Semerano L, Clavel G, Assier E, Denys A, Boissier MC. Blood vessels, a potential therapeutic target in rheumatoid arthritis ? <em>Jt<\/em> <em>Bone Spine<\/em> 2011 ; 78: 118-123. <br\/>Smolen J, Aletaha D, Redlich K. The pathogenesis of rheumatoid arthritis : new insights from old clinical data ? <em>Wet. Rev. Rheumatol.<\/em> 2012 ; 8 : 235\u201343.<br\/>St-Laurent-Thibault C, Arseneault M, Longpre F, Ramassamy C. Tyrosol and hydroxytyrosol, two main components of olive oil, protect N2a cells against amyloid-b-induced toxicity. Involvement of the NF-\u03ba\u03b2 signaling. <em>curr. Alzheimer&#8217;s Res. <\/em>2011 ; 8 : 543\u2013551.<br\/>Strand V, Kimberly R, Isaacs J. Biologic therapies in rheumatology: lessons learned, future directions. <em>Wet. Rev. Drug Discov.<\/em> 2007 ; 6 : 75\u201392.<br\/>Ruiz-Esquide V, Sanmarti R. Tobacco and Other Environmental Risk Factors in Rheumatoid Arthritis. <em>Rheumatol Clin. <\/em>2012 ; 8 : 342\u2013350.<br\/>isioli F, Galli C, Bornet F, Mattei A, Patelli R, Galli G, <em>et al.<\/em> Olive oil phenolics are dose- dependently absorbed in humans. <em>FEBS<\/em> <em>Lett.<\/em> 2000 ; 468 :159\u2013160.<br\/>Visioli F, Galli C, Grande S, Colonnelli K, Patelli C, Galli G, <em>et al<\/em> . Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration. <em>J. Nutr. <\/em>2003 ; 133 : 2612\u20132615.<br\/>Wells G, Becker JC, Teng J, Dougados M, Schiff M, Smolen J, <em>et al. <\/em>Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythrocyte sedimentation rate. <em>Ann. rheumatism.<\/em> <em>This .<\/em> 2009 ; 68 : 954\u201360.<br\/>Wu HJ, Ivanov II, Darce J, Hattori K, Shima T, Umesaki Y, <em>et al<\/em> . Gutresiding segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. <em>Immunity<\/em> 2010 ; 32: 815-827.<br\/>Zhang X, Cao J, Jiang L, Zhong L. Suppressive effects of hydroxytyrosol on oxidative stress and nuclear Factor-kappa activation in THP\u20101 cells. <em>bio. pharm. bull. <\/em>2009a ; 32 : 578\u2013582.<br\/>Zhang X, Cao J, Zhong L. Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells. Naunyn Schmiedebergs <em>Arch. Pharmacol. <\/em>2009B ; 379 : 581\u20136.<br\/>Markin D, Duek L, Berdicevsky I, \u201cIn vitro antimicrobial activity of olive leaves\u201d, Mycoses, Volume 46, Issue 3-4, pages 132\u2013136, March 2003<br\/>Serafini M, Laranjinha JA, Almeida LM, Maiani G, \u201cInhibition of human LDL lipid peroxidation by phenol-rich beverages and their impact on plasma total antioxidant capacity in humans\u201d, Journal Nutr. Biochem, Issue 11 pages 585-590, 2000<br\/>Khayyal MT et al., \u201cBlood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats\u201d Arzneimittelforschung 52(11):797-802, 2002<br\/>Manna C, Migliardi V, Gollino P, SCognamiglio A, Galletti P, Chiariello M, Zoppia V. ,\u201cOleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion\u201d Journal Nutr Biochem, Aug 2004;15(8):461-6 , 2004<br\/>Bao J, Zhang DW, Zhang JZ, Huang PL, Lee-Huang S, \u201cComputational study of bindings of olive leaf extract (OLE) to HIV-1 fusion protein gp41.\u201d FEBS Lett. 2007 Jun 12;581(14):2737-42. Epub 2007 May 21<br\/>Jemai H. et al., \u201cLipid-lowering and antioxidant effects of hydroxytyrosol and its triacetylated derivative recovered from olive tree leaves in cholesterol-fed rats, Journal Agric Food Chem. Issue 56(8):2630-6, 2008<br\/>Yamada K, Ogawa H, Hara A, Yoshida Y, et al, \u201cMechanism of the antiviral effect of hydroxytyrosol on influenza A virus including H1N1, H3N2, H5N1, H9N2\u201d Antiviral Res. 2009 Jul;83(1):35-44. doi: 10.116\/j.antiviral.2009.03.002. Epub 2009 Mar 24<br\/>Jemai H. et al., \u201cAntidiabetic and Antioxidant Effects of Hydroxytyrosol and Oleuropein from Olive Leaves in Alloxan-Diabetic Rats\u201d J Agric Food Chem, 2009 Oct 14;57(19):8798-804<br\/>Vlassios Goulas, Vassiliki Exarchou Anastassios N. Troganis Eleni Psomiadouet al, \u201cPhytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells\u201d, Molecular Nutrition &amp; Food Research, Volume 53, Issue 5, Pages 600-608, 2009<br\/>Poudyal H. Et al., \u201cOlive Leaf Extract Attenuates Cardiac, Hepatic, and Metabolic Changes in High Carbohydrate-, High Fat-Fed Rats\u201d J Nutr. 2010<br\/>J. Munoz-Marin et al, \u201cCytoprotective effect of hydroxytyrosyl alkyl ether derivatives after oral administration to rats in a model of glucose-oxygen deprivation in brain slices.\u201d, Journal of Agricolture Food Chem. 60(31):7659-64, 2012<br\/>Castaner O. et al. \u201cProtection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humans\u201d, Journal Clin Nutr. 2012 Mar 21<br\/>M. Kostomoiri, A. Fragkuoli, M. Sagnou et at, \u201cOleuropein, an Anti-oxidant Polyphenol Constituent of Olive Promotes -Secretase Cleavage of the Amyloid Precursor Protein\u201d, Cell Mol Neurobiol., 33(1): 147-54 , 2013.<\/p>\n\n<h2 class=\"wp-block-heading\">lList of literature and scientific works<\/h2>\n\n<p><strong><br\/>Abbey M, Nestle PJ &amp; Baghurst PA (1993). <\/strong><br\/>Antioxidant vitamins and low density lipoprotein oxidation. <em>American Journal of Clinical Nutrition.<\/em>  58, 52.<\/p>\n\n<p><strong>Aeschbach R, Loliger J, Scott BC, Murcia A, Butler J, Halliwell<\/strong> <strong>B, Aurome OI (1994).<\/strong> <br\/>Antioxidant actions of tymol, carvacrol, 6-gingerolo, zingerone and hydroxytyrosol. <em>Food and Chemical Toxicology<\/em> . 32 : 31\u201336.<\/p>\n\n<p><strong>Amanda L, Clark, Kathryn Mansfield Matera (2010). <\/strong><br\/>Effect of unsaturation in fatty acids on the binding and oxidation by myeloperoxidase: Ramifications for the initiation of atherosclerosis. <em>Bioorganic &amp;<\/em> <em>Medicinal Chemistry Letters.<\/em> 20 : 5643\u20135648.<\/p>\n\n<p><strong>Andrikopoulos N, Hassapidou M, Manoukas A (1989)<\/strong> . <br\/>The Tocopherol Content of Greek Olive Oils. <em>J. Sci. Food Agric. <\/em>46 : 503-509.<\/p>\n\n<p><strong>Anon (1983). <\/strong><br\/>Presencia Historica del Aceite de Oliva, in (Cabrera,FB,ed), Las Raices del Aceite de Oliva, Ministerio de Agricultura, Servicio de Publicaciones Agrarias, Madrid.<\/p>\n\n<p><strong>Aparicio R., Luna G (2002). <\/strong><br\/>Characterization of Monovarietal Virgin Olive Oils. <em>EUR. J. Lipid Sci. technology. <\/em>104 : 614-627.<\/p>\n\n<p><strong>Aroma OI (1994). <\/strong><br\/>Nutrition and health aspects of free radicals and antioxidants. <em>Food and Chemical Toxicology. <\/em>32 : 671\u2013683.<\/p>\n\n<p><strong>Aruoma OI, Deiana M, Jenner A, Halliwell B, Harparkash K, Banni<\/strong> <strong>S, Corongiu FF, Dessi MA, Aeschbach R (1998).<\/strong> <br\/>Effect of hydroxytyrosol found in extravirgin olive oil on DNA damage and on low-density lipoprotein oxidation. <em>Journal of Agricultural and Food Chemistry<\/em> . 46 : 5181\u20135187.<\/p>\n\n<p><strong>Baccouri O, Guerfel M, Baccouri B, Cerretani L, Bendini A, Lercker<\/strong> <strong>G, Zarrouk M, Daoud Ben Miled D (2008)<\/strong> . <br\/>Chemical composition and oxidative stability of Tunisian monovarietal virgin olive oils with regard to fruit ripening. <em>Food Chemistry. <\/em>109 : 743\u2013754.<\/p>\n\n<p><strong>Bai C, Yan X, Takenakay M, Sekiya S, Nagata T. (1998)<\/strong> . <br\/>Determination of synthetic hydroxytyrosol in rat plasma by GC\u2013MS. <em>Journal of<\/em> <em>Agricultural and Food Chemistry.<\/em> 46 : 3998\u20134001.<\/p>\n\n<p><strong>Beauchamp G, Keast R, Morel D (2005). <\/strong><br\/>Ibuprofen-like Activity in Extra Virgin Olive Oil. <em>Nature<\/em> . 437 : 45-46.<\/p>\n\n<p><strong>Belitz HD, Grosch W, Schieberle P (2004). <\/strong><br\/>Food Chemistry (3rd edition). Berlin : Springer Verlag.<\/p>\n\n<p><strong>Belkner J, Wiesner R, Rathman J, (1993). <\/strong><br\/>Oxygenation of Lipoproteins by Mammalian Lipoxygenases. <em>EUR. J. Biochem. <\/em>213 : 251-261.<\/p>\n\n<p><strong>Beltran G, Aguilera A, del Rio C, (2005). <\/strong><br\/>Influence of Fruit Ripening Process on the Natural Antioxidant Content of Hojiblanca Virgin Olive Oils. food chem. 89 : 207-215.<\/p>\n\n<p><strong>Ben Sassi A, Boularbah A, Jaouad A, Walker G, Boussaid A<\/strong> <strong>(2006).<\/strong> <br\/>A comparison of Olive oil Mill Wastewaters (OMW) from three different processes in Morocco. <em>Process Biochemistry. <\/em>41 (1) : 74\u201378.<\/p>\n\n<p><strong>Bendini A, Cerretani L, Carrasco-Pancorbo A, Maria G\u00f3mezCaravaca<\/strong> <strong>A, Segura-Carretero A, Fern\u00e1ndez-Guti\u00e9rrez A and G Lercker<\/strong> <strong>(2007).<\/strong> <br\/>Phenolic Molecules in Virgin Olive Oils : a Survey of Their Sensory Properties, Health Effects, Antioxidant Activity and Analytical Methods. An Overview of the Last Decade. <em>Molecules<\/em> . 12 : 1679-1719.<\/p>\n\n<p><strong>Benkhalti F, Prost J, Paz E, Perez-Jimenez F, El Modafar C, El<\/strong> <strong>Boustani E (2002).<\/strong> <br\/>Effects of feeding virgin olive oil or their polyphenols on lipid of rat liver. <em>Nutrition Research. <\/em>22 : 1067\u20131075.<\/p>\n\n<p><strong>Bianco A, Chiacchio M, Grassi D (2006). <\/strong><br\/>Phenolic Components of Olea europaea : Isolation of New Tyrosol and Hydroxytyrosol Derivatives. <em>food chem. <\/em>95 : 562-565.<\/p>\n\n<p><strong>Bianco A, Coccioli F, Guiso M (2001). <\/strong><br\/>Presence in Olive Oil of a New Class of Phenolic Compounds : Hydroxyl Isochromans. <em>food chem. <\/em>77 : 405-411.<\/p>\n\n<p><strong>Bisignano G, Tomaino A, Lo Cascio R, Crisafi G, Uccella N, Saija A<\/strong> <strong>(1999).<\/strong> <br\/>On the in vitro antimicrobial activity of oleuropein and hydroxytyrosol. <em>Journal of Pharmacy and Pharmacology. <\/em>51 : 971\u2013974.<\/p>\n\n<p><strong>Blazquez-Martinez JM (1996). <\/strong><br\/>History of Olive Tree, The World Olive Encyclopaedia, IOOC. Madrid, pp19-54.<\/p>\n\n<p><strong>Blekas G, Psomiadou E, Tsimidou M (2002). <\/strong><br\/>On the Importance of Total Polar Phenols to Monitor the Stability of Greek Virgin Olive Oil. <em>EUR.<\/em> <em>J. Lipid Sci. technology. <\/em>104 : 340-346.<\/p>\n\n<p><strong>Bonanome A, Pagnan A, Biffanti S (1992). <\/strong><br\/>Effect of Dietary Monounsaturated and Polyunsaturated Fatty Acids on the Susceptibility of Plasma Low Density Lipoproteins to Oxidative Modification. <em>arterioscler.<\/em> <em>Thromb. <\/em>12 : 529-533.<\/p>\n\n<p><strong>Bonanome A, Pagnan A, Caruso D, Toia A, Xamin A, Fedeli E,<\/strong> <strong>Berra B, Zamburlini A, Ursini F, Galli G, (2000).<\/strong> <br\/>Evidence of postprandial absorption of olive oil phenols in humans. Nutrition, <em>Metabolism<\/em> <em>and Cardiovascular Diseases<\/em> . 10 : 111\u2013120.<\/p>\n\n<p><strong>Boskou D (1996). <\/strong><br\/>Olive oil : Chemistry and Technology. <em>AOCS Press,<\/em> <em>Champaign.<\/em> IL: 52\u201383.<\/p>\n\n<p><strong>Boskou D, In. 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EUR. J. Clin. invest. 35 : 421\u2013424.<\/p>\n\n<p><strong>Perez-Jimenez F, Castro P, Lopez-Miranda J (1999). <\/strong><br\/>Circulating levels of endothelial function are modulated by diet y monounsaturated fat. <em>Atherosclerosis<\/em> . 145 : 351\u2013358.<\/p>\n\n<p><strong>Perez-Jim\u00e9nez F, Delgado Lista J, Perez-Mart\u00ednez P, Lopez-Segura<\/strong><\/p>\n\n<p><strong>F, Fuentes F, Cortes B, Lozano A, Lopez-Miranda J (2006).<\/strong><br\/>Olive oil and haemostasis : a review on its healthy effects. <em>Public Health<\/em> <em>Nutrition.<\/em> 9(8A) : 1083\u20131088.<\/p>\n\n<p><strong>Perrin J (1992). <\/strong><br\/>Minor Components and Natural Antioxidants of Olives and Olive Oils. <em>Rev. Franc.<\/em><\/p>\n\n<p><strong>Pezzuto J.M. (1997). <\/strong><br\/>Plant derived anticancer agents. <em>Biochemical<\/em> <em>Pharmacology<\/em> . 53 : 121\u2013133.<\/p>\n\n<p><strong>Princen HMG, van Poppel G, Vogelazang C, Buytenhek R, Kok<\/strong> <strong>FJ (1992).<\/strong> <br\/>Supplementation with vitamin E but not b-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro Effect of Cigarette Smoking. <em>Arteriosclerosis and Thrombosis. <\/em>12 : 554-562.<\/p>\n\n<p><strong>Psaltopoulou T, Naska A, Ofranos P (2004). <\/strong><br\/>Olive oil, the Mediterranean diet, and arterial blood pressure : the Greek European Prospective Investigation into Cancer and Nutrition (EPIC) study. <em>am. J. Clin.<\/em> <em>Nutr. <\/em>80 : 1012\u20131018.<\/p>\n\n<p><strong>Psomiadis E, Karakostas K, Blekas G (2003). <\/strong><br\/>Proposed Parameters for Monitoring Quality of Virgin Olive Oil (Koroneiki cv). <em>EUR. J. 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Pharmacological <em>Research<\/em> . 31: 275\u2013279.<\/p>\n\n<p><strong>Scaccini C, Nardini M, D&#8217;Aquino M, Gentili V, Di Felice M, Tomassi<\/strong> <strong>G (1992).<\/strong> <br\/>Effect of dietary oils on lipid peroxidation and on antioxidant parameters of rat plasma and lipoprotein fractions. <em>Journal of<\/em> <em>Lipid Research.<\/em> 33 : 627\u2013633.<\/p>\n\n<p><strong>Scania P, Casu M, Lai A (1999). <\/strong><br\/>Recognition and Quantitation of Cis-vaccenic and Eicosenoic Fatty Acids in Olive Oils by C-13 Nuclear Magnetic Resonance Spectroscopy. <em>Lipids<\/em> . 34 : 757759.<\/p>\n\n<p><strong>Servilism M, Piacquadio P, De Stefano G (2002). <\/strong><br\/>Influence of a New Crushing Technique on the Composition of the Volatile Compounds and Related Sensory Quality of Virgin Olive Oil. <em>EUR. J. 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San Diego: Academic Press, 152-178.<\/p>\n\n<p><strong>Smith T, Yang G, Serial D (1998). <\/strong><br\/>Inhibition of 4-(methylnitrosamino)1-(3-pyridyl)-1-butanone-induced Lung Tumorigenesis by Dietary Olive Oil and Squalene. <em>Carcinogenesis<\/em> . 19 : 703-706.<\/p>\n\n<p><strong>Solfrizzi V, Colacicco AM, D&#8217;Introno A, Capurso C, Torres F, Rizzo<\/strong> <strong>C, Capurso A, Panza F, (2006).<\/strong> <br\/>Dietary intake of unsaturated fatty acids and age-related cognitive decline : a 8.5-year follow up of the Italian longitudinal study on aging. <em>neurobiology. ageing. <\/em>27 : 1694\u20131704.<\/p>\n\n<p><strong>Solfrizzi V, Colacicco AM, D&#8217;Introno A, Capurso C, Torres F, Rizzo<\/strong> <strong>C, Capurso A, Panza F, (2006).<\/strong> <br\/>Dietary intake of unsaturated fatty acids and age-related cognitive decline : a 8.5-year follow up of the Italian longitudinal study on aging. <em>neurobiology. ageing. <\/em>27 : 1694\u20131704.<\/p>\n\n<p><strong>Solfrizzi V, Panza F, Capurso A (2003). <\/strong><br\/>The role of diet in cognitive decline. <em>J. Neural. transm. <\/em>110 : 95\u2013110.<\/p>\n\n<p><strong>Solfrizzi V, Panza F, Torres F, Mastroianni F, Del Parigi A, Venezia<\/strong> <strong>A, Capurso A, (1999).<\/strong> <br\/>High monounsaturated fatty acids intake protects against age-related cognitive decline. <em>neurology<\/em> . 52: 1563\u20131569. <\/p>\n\n<p>205 \u2022\u2022\u2022<\/p>\n\n<p><strong>The effects of olive oil on health \u2022\u2022\u2022<\/strong><\/p>\n\n<p><strong>Speroni E, Guerra MC, Minghetti A, Crespi-Perello N, Pasini P,<\/strong> <strong>Piazza F, Roda A (1998).<\/strong> <br\/>Oleuropein evaluated in vitro and in vivo as an antioxidant. <em>Phytotherapy Research. <\/em>12 : 98\u2013100.<\/p>\n\n<p><strong>Sumpio B, Cordova A, Berke-Schlessel D (2006). <\/strong><br\/>Green tea, the \u201cAsian paradox,\u201d and cardiovascular disease. <em>J. Am. col. Surg.<\/em> 202 :813\u2013825.<\/p>\n\n<p><strong>Sung B, Jin Jeong KI, Seok Song YE, Jin Son M, Pal Yu B, Young<\/strong> <strong>Chung H (2005).<\/strong> <br\/>cDNA representational difference analysis used in the identification of genes related to the aging process in rat kidney. <em>Mechanisms<\/em> <em>of Aging and Development.<\/em> 126 : 882\u2013891.<\/p>\n\n<p><strong>Tanaka T, Makita H, Kawamori T, Kawabata K, Mori H, Murakami<\/strong> <strong>A, Satoh K, Hara A, Ohigashi H, Koshimizu K (1997).<\/strong> <br\/>A xanthine oxidase inhibitor acetoxychavicol acetate inhibits azoxymethane-induced colonic aberrant crypt foci in rats. <em>Carcinogenesis<\/em> . 18: 1113\u20131118.<\/p>\n\n<p><strong>Tiscornia E, Fiorina N, Evangelisti F (1982). <\/strong><br\/>Chemical Composition of Olive Oil and Variations Induced by Refining. <em>riv. Italy. sost. Grasse.<\/em>  59 : 519-555.<\/p>\n\n<p><strong>Trichopoulou A, Costacou T, Bamia C (2003). <\/strong><br\/>Adherence to a Mediterranean Diet and Survival in a Greek Population. <em>N. Engl. J. Med.<\/em>  348 : 2599-2608.<\/p>\n\n<p><strong>Trichopoulou A, Orfanos P, Norat T (2005). <\/strong><br\/>Modified Mediterranean Diet and Survival : EPIC-Elderly Prospective Cohort Study. <em>Bmj.<\/em>  330 : 991.<\/p>\n\n<p><strong>Tuck KL, Freeman MP, Hayball PJ, Stretch GL, Stupans I (2001).<\/strong><br\/>The in vivo fate of hydroxytyrosol and tyrosol, antioxidant phenolic constituents of olive oil, after intravenous and oral dosing of labeled compounds to rats. <em>Journal of Nutrition. <\/em>131 : 1993\u20131996.<\/p>\n\n<p><strong>Tuck KL, Hayball PJ (2002). <\/strong><br\/>Major phenolic compounds in olive oil : Metabolism and health effects. <em>The Journal of Nutritional Biochemistry.<\/em>  13 : 644.<\/p>\n\n<p><strong>Tuck KL, Hayball PJ, Stupans I (2002). <\/strong><br\/>Structural characterization of the metabolites of hydroxytyrosol, the principal phenolic component in olive oil, in rats. <em>Journal of Agricultural and Food Chemistry. <\/em>50 : 2404\u20132409.<\/p>\n\n<p><strong>Uccella N (2001). <\/strong><br\/>The olive biophenols : hedonic-sensory descriptors of evoo and wotos in the Mediterranean aliment culture. In Food Flavors and Chemistry: Advances of the New Millennium. AH Spanier, F. Shahidi, TH Parliment, CJ Mussinan, CT Ho, E. TratrasContis Eds. <em>The Royal Society of Chemistry Publishers,<\/em> Cambridge, UK. 253-265.<\/p>\n\n<p><strong>Van Dyke DR, Saltman P (1996). <\/strong><br\/>Hemoglobin : a mechanism for the generation of hydroxyl radicals. <em>Free Radical Biology and Medicine.<\/em> 20 : 985\u2013989.<\/p>\n\n<p><strong>Visioli F, Bellomo G, Montedoro G, Galli C (1995). <\/strong><br\/>Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. <em>Atherosclerosis<\/em> . 117 :25\u201332.<\/p>\n\n<p><strong>Visioli F, Bellomo G, Montedoro GF, Gallic (1995a). <\/strong><br\/>Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. <em>Atherosclerosis<\/em> . 117 : 25\u201332.<\/p>\n\n<p><strong>Visioli F, Bellomo G, Montedoro GF, Gallic (1995a). <\/strong><br\/>Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. <em>Atherosclerosis<\/em> . 117 : 25\u201332.<\/p>\n\n<p><strong>Visioli F, Caruso D, Plasmati E, Patelli R, Mulinacci N, Romani A,<\/strong> <strong>Galli G, Galli C (2001).<\/strong> <br\/>Hydroxytyrosol, as a component of olive mill waste water, is dose-dependently absorbed and increases the antioxidant capacity of rat plasma. <em>Free Radical Research. <\/em>34 : 301\u2013305.<\/p>\n\n<p><strong>Visioli F, Galli C (1998). <\/strong><br\/>The effect of minor constituents of olive oil on cardiovascular disease : new findings. <em>Nutr. Rev. <\/em>56 : 142\u2013147.<\/p>\n\n<p><strong>Visioli F, Galli C (1998b). <\/strong><br\/>The effect of minor constituents of olive oil on cardiovascular disease : new findings. <em>Nutrition Reviews. <\/em>56 : 142\u2013147.<\/p>\n\n<p><strong>Visioli F, Galli C (2001). <\/strong><br\/>Antiatherogenic components of olive\/olive oil. Current <em>Atherosclerosis Reports.<\/em> 3 : 64\u201367.<\/p>\n\n<p><strong>Visioli F, Galli C (2003). <\/strong><br\/>Olives and their production waste products as sources of bioactive compounds. <em>Current Topics in Nutraceutical Research.<\/em> 1:85\u201388.<\/p>\n\n<p><strong>Visioli F, Galli C (2003). <\/strong><br\/>Olives and their production waste products as sources of bioactive compounds. <em>Current Topics in Nutraceutical Research.<\/em> 1:85\u201388.<\/p>\n\n<p><strong>Visioli F, Galli C, Bonnet F, Mattei A, Patelli R, Galli G, Caruso D<\/strong> <strong>(2000).<\/strong> <br\/>Olive oil phenolics are dose-dependently absorbed in humans. <em>FEBS Letters. <\/em>468: 159\u2013160.<\/p>\n\n<p><strong>Vissers MN, Zock PL, Roodenburg AJC, Leenen R, Katan MB<\/strong> <strong>(2001).<\/strong> <br\/>Olive oil phenols are absorbed in humans. <em>American Society for<\/em> <em>Nutritional Sciences.<\/em> 409\u2013417.<\/p>\n\n<p><strong>Wiseman SA, Mathot JNJ, De Fouw NJ, Tijburg LBM (1996).<\/strong><\/p>\n\n<p>Dietary non-tocopherol antioxidants present in extra virgin olive oil increase the resistance of low density lipoproteins to oxidation in rabbits. <em>Atherosclerosis<\/em> . 120 : 15\u201323.<\/p>\n\n<p><strong>Witztum JL, Steinberg D (2001). <\/strong><br\/>The Oxidative Modification Hypothesis of Atherosclerosis: Does it Hold for Humans? <em>Trends Cardiovasc<\/em> <em>Med.<\/em> 11:93-102.<\/p>\n\n<p><strong>Yermilov V, Rubio J, Ohshima H (1995). <\/strong><br\/>Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination. <em>FEBS Letters. <\/em>376 : 207\u2013210.<\/p>\n\n<p><strong>Zhu LI, Liu Z, Feng ZHao J, Shen WEI, Li X, Sun L, Sharman E,<\/strong> <strong>Wang Y, Wertz K, Weber P, Shi X, Liu J (2010).<\/strong> <br\/>Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Several articles on polyphenols and olive leaf extract. Written by Bart Maes. The organic veggie man. His articles always have [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":5962,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1326],"tags":[277,1425,1386,1378,804],"ads-targeting":[1324],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.13 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Resources and Scientific References on Polyphenols<\/title>\n<meta name=\"description\" content=\"Bart Maes wrote 22 pages on the freedom of heath website about polyphenols and olive leaf extract. 200 Citations as scientific support.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.bartmaes.eu\/en\/polyphenols\/sources-and-references-about-polyphenols\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" 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